The Four Best Ways to Open CDXML Files

The first way you should always try to open file extension CDXML is to double-click it, but when that doesn’t work, there are a few other things you can try. There are lots of programs that can open different file extensions, and there are some simple ways you can tell which one to use.

Pick the Right Program

Start by choosing the right program to open your CDXML file. The most common program used to open CDXML files is listed below. At a minimum, this program should be able to open your CDXML file:

  • ChemDraw XML ChemDraw Format

Note the File Type

Other programs may be able to open your CDXML file, depending on the type of file it is. You can find the file type listed in the file’s properties. On a Windows PC, right-click the file, click "Properties", then look under “Type of File.” On a Mac computer, right-click the file, click “More Info,” then look under “Kind”.


Tip: If it’s the CDXML file extension, it probably falls under the Developer Files type, so any program used for Developer Files should open your CDXML file.

Ask the Developer

Contacting the software developer is another easy way to get help opening a CDXML file. You can find the developers for the most common programs used to open CDXML files in the list below.

Software Developer
ChemDraw XML ChemDraw Format Unknown

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